The Data Coordinating Center (DCC) is based at the University of Michigan and will provide leadership regarding the analytical, statistical, and data management for the THRIVE study, including areas such as study design and oversight, enrollment reporting, statistical analysis, and data collection.
The Clinical Coordinating Center (CCC) has representation from several THRIVE sites (e.g. Washington University, University of Michigan, University of Pennsylvania, Stanford University) and will manage processes related to patient enrollment and study coordinator training in order to ensure patient-centered and rigorous trial execution.
Patient Partnership & Engagement is a crucial component of the THRIVE trial. The patient partners bring lived experiences and will be engaged in planning activities throughout all phases of the trial. To operationalize this an intricately designed structure has been developed including:
The Patient Partnership Leadership Center (PPLC) will serve as an innovation and methods core to support and inform all patient partnership activities
The Patient & Caregiver Engagement Working Group will provide oversight, operational direction, and ongoing technical, logistical, and administrative support for THRIVE patient engagement work. This work will occur through:
- A Patient & Caregiver Panel to provide input feedback and guidance to THRIVE research, communication, outreach and engagement activities.
- Site-level patient engagement activities to be developed as a component of the full-scale trial
- Additional patient engagement efforts to be determined over the course of the study