Explore the THRIVE operational structure, outlining the roles and responsibilities of each coordinating group, the systems that support collaboration across participating sites, and the processes that maintain consistent communication, data flow, and trial oversight.
Administrative Structure
THRIVE is built on a multi‑layered, collaborative leadership and working‑group structure designed to drive coordination, accountability, and scientific rigor across every phase of the trial. This integrated framework brings together experts, stakeholders, and community partners to ensure that decision‑making is transparent, operations are efficient, and the trial is positioned for long‑term success.
Coordination & Engagement
Data Coordinating Center (DCC)
The DCC is based at the University of Michigan and will provide leadership regarding the analytical, statistical, and data management for the THRIVE study, including areas such as study design and oversight, enrollment reporting, statistical analysis, and data collection.
DCC Program Manager
Chelsea Cloyd, MBA
DCC/MPOG Program Manager
Shelley Vaughn, MPH
DCC Faculty Lead
Sachin Kheterpal, MD MBA
Clinical Coordinating Center (CCC)
The CCC has representation from several THRIVE sites (e.g. Washington University, University of Michigan, University of Pennsylvania, Stanford University) and will manage processes related to patient enrollment and study coordinator training in order to ensure patient-centered and rigorous trial execution.
CCC Program Manager
Laura Swisher, MS
CCC Co-Investigator
Bethany Pennington, PharmD, BCPS
CCC Faculty Lead
Michael Avidan, MBBCh
Engagement Coordinating Center
Patient partnership and engagement is a crucial component of the THRIVE trial. The patient partners bring lived experiences to the trial, and will be engaged in planning and operational activities throughout all phases of the trial. To operationalize this, a thoughtfully designed structure has been developed including:
The Engagement Coordinating Center (ECC) will serve as an innovation and methods core to support and inform all patient partnership activities
The Patient & Caregiver Engagement Working Group will provide oversight, operational direction, and ongoing technical, logistical, and administrative support for THRIVE patient engagement work. This work will occur through:
Patient Partnership Program Manager
Mara Bollini, BSN, MHA
Patient Partnership Faculty & Patient Leads
Mark Neuman, MD
Hugo Campos
Larry Chu, MD MS
Amy Price, DPhil
Roya Saffary, MD
