July 2022

Issue #6

Important Announcements

● ClinicalTrials.gov registration is live!

● Visit and share the MPOG THRIVE website link https://mpog.org/thrive-info/

● All THRIVE Dropbox folder - You should have received an invitation to this folder, but you may be

required to create a Dropbox account or verify your email address. Email David Clark with any

access issues.

Coordinating Center Updates

Clinical Coordinating Center

● WUSTL sIRB approved THRIVE Center

application

● Full Phase enrollment sites chosen and

contacted

● August goal for first patient enrolled

● THRIVE presentations to key stakeholder

groups (nurses, anesthesia technicians,

anesthesia clinicians, surgeons) underway

● Clinician Educational Resources will be

housed on the THRIVE clinician facing

webpages - see THRIVE Team Spotlight

for more information.

Data Coordinating Center

● Undergoing testing for dry run testing of

entire software suite including patient facing

component (MyDataHelps), Recruitment

Management/Randomization (MQUARK) and

EHR Data Flow (MPOG Patient Matching

Application)

● Randomization algorithm implementation

being tested

● THRIVE clinician facing webpages on MPOG

website are active - https://mpog.org/thrive-

info/

● Patient-facing website being developed, will

be seeking input on content shortly.

Patient Partnership Leadership Center

●

Intake form for any working group or Center needing Patient Panel feedback has been developed

with the goal of it being completed and documents (if applicable) distributed and shared with the

Patient Partner Panel 1-week prior to their scheduled meeting, link here: THRIVE Patient Partner

Panel Feedback Request Form

● Next Patient Partner Panel meeting scheduled for July 28

with a focus on PP educational needs

and THRIVE Working Group overview.

Funded by

Contract 2020C3-21106

THRIVE Team Spotlight

A tremendous collaborative effort led by our University of Michigan colleagues has made the MPOG

clinician-facing webpages on the MPOG website possible. These webpages have been shared through the

CCC updates in prior newsletters however the focus on the relevant educational components that are two

of the five key drivers for the success of THRIVE including shared understanding & fidelity of interventions

is worth time in the spotlight. As preparation continues for initiating enrollment in August, clinician

education is at the forefront and these resources are a primary focus for all clinical providers and

healthcare team members who will be caring for THRIVE patient participants.

All THRIVE team members are encouraged to visit https://mpog.org/thrive-clinician-educational-

resources/ to click through, read/watch the educational content provided to clinician partners.

Emerging & Relevant Literature

Timely brief introduction to patient reported outcomes: Weinfurt KP, Reeve BB. Patient-Reported

Outcome Measures in Clinical Research. JAMA. Published online July 15, 2022.

Do trialists, patients, and health professionals choose the same trial primary outcomes? Treweek, S.,

Miyakoda, V., Burke, D. et al. Getting it wrong most of the time? Comparing trialists’ choice of primary

outcome with what patients and health professionals want. Trials 23, 537 (2022).

In the works!

● THRIVE working groups are meeting to operationalize different aspects of the THRIVE trial - you

may be invited to participate on one or more groups

● Planning THRIVE kick-off meeting at the October ASA meeting (MPOG pre-meeting)

● This newsletter is in the process of being transitioned to MailChimp sometime this summer. The

goal will be to streamline content development and distribution.

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