Adherence to Intraoperative Antibiotic Administration
Guidelines across MPOG institutions
Amit Bardia
Assistant Professor
Dept. of Anesthesiology
Yale School of Medicine
Disclosures:
Principal Investigator of a Trial supported by an Investigational
Grant by Merck & Co.
Surgical Site Infections (SSI)
SSI are the leading cause of health care infections in
surgical patients
1
.
Estimated incidence
3
: 2-5%
Accounts for about 1.6 billion in health care related costs
2
.
1. Anderson DJ et al. Infect Control Hosp Epidemiol. 2014;35(6):605-27.
3. de Lissovoy G et al. Am J Infect Control 2009;37:387-97.
2. Bratzler DW et al. Clin Infect Dis 2004;38:1706-15
Surgical Site Infections (SSI)
Antimicrobial Prophylaxis Guidelines
Aims and Objectives
To explore factors associated with guideline based
antibiotic non adherence in this cohort.
To determine the prevalence of non-adherence to
guideline based Intraoperative antibiotic administration.
MPOG registry data from 31 centers between the dates of
01/01/2014 and 12/31/2018 was extracted to estimate the adherence
to four guideline metrics (timing prior to incision, choice, dosing,
redosing) for antibiotic administration.
Methods
Inclusion Criteria: Patients 18 years of age or older who
underwent non-cardiac surgery involving skin incision.
Exclusion Criteria:
American Society of Anesthesiologists score (ASA) 6,
missing documentation for weight, antibiotic dose, or time
of administration.
Consort Figure
Results
Results
Results
Percent non-adherence by institution.
Results
Temporal trends in adherence from 2014 to 2018.
Results
Conclusions
Significant opportunity for improvement in guideline
based Intra-operative antibiotic administration exists.
The impact of these non-adherence on surgical site
infections needs to be elucidated in future studies.
Thank you
