March 2022
Issue #2
Important Announcements
● All THRIVE Dropbox folder - You should have already received an invitation
to this folder, but you may be required to create a Dropbox account or
verify your email address. Email Chelsea Cloyd or David Clark if you are
having any access issues.
● Official PCORI contract start date is January 1, 2022
Coordinating Center Updates
Clinical Coordinating Center
● Feasibility protocol submitted to PCORI
for initial feedback
● Enrollment site application in pilot
testing
● Manual of Procedures in process
● Consent form in development
Data Coordinating Center
● Participant-facing study application design in
progress
● Research coordinator facing electronic case
report forms development ongoing
● DSMP creation in progress
Patient Partnership Leadership Center
● Patient partner, research participant,
and caregiver engagement working
group to be formed in the next month
Administrative
● Administrative & Organizational structures
● Contract is signed, effective date Jan. 1, 2022
● Subcontracting underway
In the works!
● THRIVE leadership is forming working groups to operationalize different aspects of the THRIVE trial -
you may be invited to participate on one or more groups
● The patient-facing website’s relevant domain names have been acquired
● Webpage for interested enrollment sites on MPOG website under development
Timeline - Updated
Dates
Milestone
1/1/2022 - 6/30/2023
Feasibility Study Phase - we are here
7/1/2022
Begin Dry Run enrollment to test information systems, MOP, training, etc.
8/1/2022
Begin feasibility patient enrollment (UM and WUSTL)
7/1/2023 - 6/30/2028
Full Study Phase
Emerging Literature
National Poll on Healthy Aging: Decision-Making About Elective Surgery
Surgeries to address a health problem that is not immediately life-threatening, often referred to as “elective”
surgeries, include procedures such as cataract surgery, joint replacement, and hernia repair. Several factors can
influence decisions about whether and when to have an elective surgery. In August 2021, the University of Michigan
National Poll on Healthy Aging asked a national sample of adults aged 50–80 about their decision-making around
elective surgeries.
Key Statistics from the poll:
1. Of 2,110 older adults nationwide, 64% responded
2. 64% of respondents were concerned about pain or discomfort
3. 57% of respondents were concerned about difficulty of recovery
4. Patients who chose to defer surgery or were awaiting surgery were more likely to be concerned about
surgery when compared to those who already had the surgery (64% vs 53%)
5. Overall, 67% of respondents who had an elective surgery in the last five years were very satisfied with the
outcome
Suggestion Box: tell us the kinds of updates you would like to receive!
Funded by
Contract 2020C3-21106
